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Shenzhen Simeiquan Biotechnology Co., Ltd.
Shenzhen Simeiquan Biotechnology Co., Ltd. Professional Steroid Hormone Supplier from China
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Whatsapp +86-18038176818 Weight Loss Steroids Melanotan2 MT-2 Mr.Thyen

Whatsapp +86-18038176818 Weight Loss Steroids Melanotan2 MT-2 Mr.Thyen

Brand Name : Simeiquan
Model Number : 10mg/vial
Certification : ISO9001
Place of Origin : China
MOQ : 10vials
Price : Negotiated
Payment Terms : T/T, Western Union, MoneyGram,Bit Coin
Supply Ability : 10000 vial/month
Delivery Time : Within 24 hours after receiving the payment
Packaging Details : Original Box
Product name : Melanotan 2
Contact : Mr.Thyen
With : Good Price
Linked In : Sell Steroids and Peptides
Whatsapp : +86-18038176818
Company name : Shenzhen Simeiquan Biotechnology Co.,ltd
Contact Now

Whatsapp +86-18038176818 Weight Loss Steroids Melanotan2 MT-2 Mr.Thyen


Melanotan-II (MT-II)


Product Name:Melanotan II


Melanotan-II Unit Size :10 mg/vial


Melanotan-II Unit Quantity :1 Vial


Melanotan-II Synonyms:Acetate Melanotan II


Melanotan-II Sequence: Ac-NLE-c[ASP-His-d-PHE-ARG-TRP-LYS]-NH2 Chemical Bridge Asp2-Lys7


Melanotan-II Purity (HPLC): 99.21%


Melanotan-II CAS:121062-08-6


Melanotan-II Identity (ESI-MS) :1024.18±1.0


Melanotan-II Appearance: White powder


Melanotan-II Molecular Formula: C50H69N15O9


Melanotan-II Molecular Weight: 1024.18


Melanotan-II Single Impurity (HPLC): 0.5%max


Melanotan-II density :1.43


Melanotan-II Amino Acid Composition: ±10% of theoretical


Melanotan-II Peptide Content (N%): ≥80.0%


Melanotan-II Water Content(Karl Fischer): ≤8.0%


Melanotan-II Acetate Content(HPIC): ≤10.0%


Melanotan-II Specific Rotation (20/D): -55.0~-65.0°(c=1 1%HAc)


Melanotan-II MS(ESI): Consistent


Melanotan-II Mass Balance: 95.0~105.0%


Melanotan-II density:1.43


Melanotan-II Source :Chemical Synthesis


Melanotan-II Storage :Lyophilized Melanotan II is stable at room temperature for 90 days,however it should be stored in a freezer below -8C for any extended period of time. After reconstituting Melanotan II should be refrigerated at temperatures not to exceed 36 F.


Melanotan-II Specification:


ITEM
SPECIFICATION
AppearanceWhite Crystalline Powder
Assay≥99%
Heavy Metals≤10ppm
Arsenic≤1ppm
Lead≤3ppm
Mercury≤0.1ppm
Cadmium≤1ppm
Total Plate Count≤1000cfu/g
Yeast & Mold≤100cfu/g
E.ColiNegative
SalmonellaNegative
ConclusionThe product conforms to the standard.



Melanotan-II Mechanism of action:


Melanotan II acts as a non-selective agonist of the melanocortin receptors, MC1, MC3, MC4, MC5. Like other melanocortinergic peptides, such as the melanocyte-stimulating hormones (MSHs) and afamelanotide, but unlike adrenocorticotropic hormone (ACTH), melanotan II lacks affinity for the MC2 receptor. Reported activity of the drug is as follows:


MC1 (Ki = 0.686 nM)
MC2 (Ki > 1000 nM)
MC3 (Ki = 34.1 nM)
MC4 (Ki = 6.60 nM
MC5 (Ki = 46.1 nM)


The melanogenesis produced by melanotan II is caused by activation of the MC1 receptor, whereas its sexual effects are thought to be related to its ability to activate the MC4 receptor (though the MC3 is thought to possibly also be involved). Other effects of melanotan II, mostly regarded as adverse effects, include flushing, nausea, vomiting, stretching, yawning, and loss of appetite (the last via activation of MC4).


Melanotan II produces bremelanotide, which, comparatively, is reported to be approximately 50-fold more potent as an inducer of sexual arousal in rats, as an active metabolite.


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